Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Rabbit, absolute alcohol, Best's*
carmine and hematoxylin stains, 612 x.
The stain used here is specific for glycogen, although the rationale for its selectivity is uncertain. For another glycogen stain see Plate 78.
Sinusoids: Vascular channels larger in diameter than ordinary capillaries but composed of a single layer of fenestrated endothelial cells separating sheets of hepatic cells.
Hepatic cells: Arranged in plates. Each cell has a distinct central nucleus. These cells may contain more than one nucleus.
Glycogen: Stored throughout the cytoplasm. Glycogen is normally stored in hepatic cells whose content varies with the functional state of the liver and the dietary intake. Glycogen is a polysaccharide, a polymer composed of many molecules of glucose. It stains red by this method.
Central vein: Center of the hepatic lobule. Smallest radicle of the hepatic vein, which receives the contents of all the sinusoids comprising the hepatic lobule. See Plates 215, 218, 219.
*Best, 1878-1920, was a German pathologist working in Dresden.
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