Brush border, basal striations proximal tubules kidney
Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Rhesus monkey, Helly's fluid,
iron hematoxylin-orange G, 1416 x.
The cells of the proximal tubule with their apical and basal specializations have the capacity to reabsorb selectively and transport metabolically valuable substances from the glomerular filtrate (e.g., glucose and amino acids), returning them to the vascular system. They also transport and secrete other substances in the lumen of the proximal tubule to be eliminated in the urine.
Nucleus: Round and large with prominent nucleolus.
Brush border: On the luminal surface of the tubule cells. Consists of microvilli that vastly increase the cellular absorptive surface.
Basal striations: Consist of rod-shaped mitochondria contained within compartments formed by specialized infoldings of the basal cell membrane.
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