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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 3 - Connective Tissue

Plate 3.43: Endochondral Ossification

Finger phalanx

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Finger phalanx

Plate 3.43: Endochondral Ossification

Human, 10% formalin, H. & E., 162 x.

Endochondral bone is a form of ossification in which an embryonal type of hyaline cartilage precedes the formation of bone. In this figure, note the change from the zone of reserve cartilage cells to the zone of hypertrophic cartilage cells. Lacunae are increased in size, and the interlacunar space is reduced in the region of the hypertrophic cells. Note the concomitant change in the perichondrium in which the inner cells change into osteogenic cells (osteoblasts) leading to the formation of the periosteal (perichondral) bone collar.

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