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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 3 - Connective Tissue

Plate 3.45: Fetal Long Bone

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed


Plate 3.45: Fetal Long Bone

Rodent, Helly's fluid, Mallory-azan, 5.5 x.

At this stage of development, the upper epiphyseal cartilage has been invaded by blood vessels and mesenchyme prior to the formation of the epiphyseal ossification center.

The diaphyseal bony collar extends to the epiphyseal plate composed of calcified cartilage. The formation and remodeling of the diaphysis can be seen to be well advanced.

The process of bone formation will not be complete, and bone growth ended, until the epiphyseal plate disappears and the marrow cavity becomes continuous throughout the bone. The blood vessels of the diaphysis, epiphyses, and metaphyses will then intercommunicate.

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