Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Human, air-dried marrow smear, Wright's stain, 1416 x.
Megakaryocyte: Giant cell characteristic of bone marrow, with a conspicuous multilobed nucleus. Cytoplasm contains fine granules. Pseudopodia extend from the cell surface and later detach to form the blood platelets. Blood platelets participate in the blood-clotting mechanism by contributing to the formation of thromboplastin, by "plugging" abnormal breaks in the endothelium of blood vessels, and by inducing the constriction of damaged blood vessels.
Red blood cells: Non-nucleated corpuscles having a circular or dumbbell-shaped appearance. Contain hemoglobin.
Lipocyte: Fat cells are constantly present in bone marrow. They have irregular outlines and are filled with lipid droplets.
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