Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Human, Helly's fluid, Mallory's stain, 1416 x.
Several branching cardiac muscle fibers are seen in this plate. Note the transverse striations characteristic of cardiac and skeletal muscle fibers. Two ovoid nuclei are seen in one fiber and are always centrally located. Nuclei are oriented in the long axis of the fiber and contain prominent nucleoli. Binucleate fibers are seen only occasionally in cardiac muscle. Adjacent to the nuclei, note the greenish-black granules of lipochrome pigment. This pigment increases with age and is thought to be a product of normal metabolic activity. See also Plate 13.
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