Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed
Cat, Helly's fluid, H. & E., 162 x.
Pacinian corpuscles are mechanoreceptors found in the pancreas of cats but not man. In man and other animals, they are readily seen in sections of the dermis from the fingers and palm of the hand, the conjunctiva, near joints, in the mesenteries, branching blood vessels, penis, urethra, clitoris, parietal peritoneum, and loose connective tissue.
The Pacinian corpuscle is a pressure receptor and responds to high-frequency vibratory stimuli. Since the corpuscle is fluid-filled, it is essentially incompressible. The corpuscle transmits mechanical stimuli, through the connective tissue lamellae and fluid, to excite the nonmyelinated receptor axon in its core.
Pacinian corpuscles vary in size, but many are large enough to be easily dissected without magnifying lenses in the fingers of man.
Inner bulbs: Transverse section of branches of terminal unmyelinated nerve endings.
Lamellae: Concentric layers of collagenous connective tissue and flattened fibroblasts.
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