Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Human, 10% formalin, H. & E., 162 x.
Skin of the finger tip is characterized by a thick cornified epithelium, an absence of hair, and an abundance of tactile corpuscles of Meissner in the dermis.
Note the thick stratum corneum; the stratum granulosum, containing keratohyalin granules; and the stratum spinosum, overlying the stratum basale. An epidermal peg is seen dividing a primary dermal papilla into secondary papillae. Note the Meissner's corpuscle in the dermal papilla. This is an oval, encapsulated touch receptor composed of flattened connective tissue stacked horizontally and a sensory nerve fiber. The sensory nerve fiber leaves the corpuscle and enters the spinal cord with the dorsal root fibers. Another component of dermal papillae is a capillary loop that supplies the overlying epithelium with nutrients and oxygen and removes metabolic waste.
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