Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Human, 10% formalin, H. & E., 50 x.
The hypodermis is a layer of subcutaneous connective tissue beneath the dermis. It is composed of connective tissue fibers disposed in all directions and continuous with those of the dermis. The density of the connective tissue elements varies in different locations, being less dense in "loose" skin (e.g., arm) and more compact where the skin is firmly attached (e.g., fingers). Groups of fat cells are also found in the hypodermis. The concentration of fat is regionally variable. In addition, the hypodermis is rich in nerve fibers and sensory receptors (Pacinian corpuscles) as well as blood vessels.
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