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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 7 - Integument

Plate 7.147 Sebaceous Gland

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Hairy skin dorsum of arm
Plate 7.147 Sebaceous Gland

Human, Helly's fluid, toluidine blue and erythrosin stains, 162 x.

Epidermis: Stratified squamous cornified epithelium of the skin.

Dermis: Connective tissue layer beneath the epidermis. Its thickness varies in different parts of the body. It is rich in collagenous and elastic fibers. The part of the dermis underlying the epithelium is called the papillary layer. The deeper part is the reticular layer, in which sebaceous glands are found. In addition, hair follicles, sweat glands, and Pacinian corpuscles occur in this layer. In the face, the striated muscles of facial expression terminate in the dermis.

Sebaceous gland: Holocrine variety of gland in which the entire cell is lost along with the secretory products. Intimately associated with hair follicles into which they drain. Composed of a group of saclike alveoli ensheathed by a thin layer of connective tissue. The alveoli are composed of stratified cuboidal or polyhedral epithelia[ cells that fill the sac. The secretion of the sebaceous gland is an oily substance (sebum) that lubricates the epidermis and hair.

Sebaceous gland cell: Note the peripheral, small cuboidal cells and the more central, larger polyhedral or spheroidal cells. Oily droplets increase with an increase in size of the cells. See Plate 83.

Nucleus: Nuclei of peripheral cells are rounded. Nuclei of centrally located cells are either shrunken or absent. This nuclear change is part of the degenerative process by which the entire cell is lost, along with its secretion product.

Hair follicle: Surrounds the hair shaft and is composed of inner epidermal epithelial elements and outer dermal connective tissue elements.

Hair shaft: Located within the follicle. The free end of the hair projects from the surface of the skin.

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