Anatomy Atlases(tm) : A digital library of anatomy information

Home | About | FAQ | Reviews | Search

Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 10 - Digestive System

Plate 10.203 Ileum: Lymphocytic aggregation

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Lymphocytic aggregation

Plate 10.203 Ileum: Lymphocytic aggregation

Human, 10% formalin, H. & E., 96 x.


Lymphocytes leave lymphoid organs to populate Peyer's patches of the ileum and elsewhere. B lymphocytes that arise from the bone marrow are found in Peyer's patches. When activated, they give rise to lymphoblasts, which differentiate into plasma cells and small lymphocytes called memory cells. Plasma cells migrate through the lamina propria to the basal lamina of the epithelial surface where they secrete IgA (see section on lymphatic system), which is transported through the overlying epithelium to provide antibody at the epithelial surface of the organ. Other immunoglobulin (IgM, IgG)- secreting cells are also present but are fewer in number.

The epithelium overlying the massive aggregation of (primarily) B lymphocytes is squamous to low columnar. The epithelial cells are called M cells and are thought to endocytose antigens from the lumen of the organ, transport them through their cytoplasm, and discharge them so that they may make contact with the active, underlying lymphocytes.

Next Page | Previous Page | Section Top | Title Page

Home | About Us | FAQ | Reviews | Contact Us | Search

Anatomy Atlases is curated by Michael P. D'Alessandro, M.D. and Ronald A. Bergman, Ph.D.

Please send us comments by filling out our Comment Form.

All contents copyright © 1995-2018 the Author(s) and Michael P. D'Alessandro, M.D. All rights reserved.

"Anatomy Atlases", the Anatomy Atlases logo, and "A digital library of anatomy information" are all Trademarks of Michael P. D'Alessandro, M.D.

Anatomy Atlases is funded in whole by Michael P. D'Alessandro, M.D. Advertising is not accepted.

Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.

The information contained in Anatomy Atlases is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.