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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 10 - Digestive System

Plate 10.213 Pancreas

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Acinar and centroacinar cells

Plate 10.213 Pancreas

Human, 10% formalin, toluidine blue and eosin stains, 612 x.


Acinar cells: Cells forming the alveoli or acini of the pancreas. Pyramid-shaped cells arranged around a central lumen. Alveoli are packed close together with intervening delicate connective tissue. Cytoplasm of individual acinar cells is densely basophiiic, and the nucleus is spherical and basally located. The cytoplasmic basophilia (RNA) is a reflection of the specialization of these cells for protein synthesis and secretion of zymogen.

Centroacinar cells: Belong to the duct system. Smaller than the surrounding acinar cells. Centroacinar cells stain lighter than acinar cells and are squamous to cuboidal. Centroacinar cells occur only in the pancreas.

See Plate 26.

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Anatomy Atlases is curated by Michael P. D'Alessandro, M.D. and Ronald A. Bergman, Ph.D.

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