Plate 13.248 Ovary: Cortical Region
Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Rhesus monkey, Helly's fluid, H. & E., 50 x.
Primordial follicles: Consist of an immature ovum surrounded by a single layer of low cuboidal or flattened epithelium (follicular or granulosa cells). Note the distribution in peripheral layers of the cortex.
Maturing follicle: Note the multilayered follicular cells, the increased size, the eccentric position of the developing ovum, and the prominent connective tissue capsule. Maturing follicles occupy deeper zones of the cortex. Note the vesicular nucleus and the deeply staining small nucleolus. The oocyte is pushed to the side of the follicle by the accumulation of follicular fluid.
Atretic follicle: Follicles that do not reach maturity degenerate and are called atretic follicles. The nucleus becomes pyknotic and later fragments. Follicular cells also degenerate. Atretic follicles are later resorbed and are replaced by a connective tissue stroma. The zona pellucida of an atretic follicle stains deeply and may persist by itself in the stroma.
Corpus albicans: A hyaline scar resulting from the degeneration of a corpus luteum of ovulation.
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