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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 15 - Endocrine Glands

Plate 15.281 Hypophysis

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Anterior, intermediate, and posterior lobes

Plate 15.281 Hypophysis

Rat, 10% formalin,
Gomori's chrome alum hematoxylin and phloxine stains, 162 x.


The anterior lobe is made of anastomosing cords and plates separated by capillaries. Several trophic hormones are produced in this lobe: somatotropin, follicle-stimulating hormone, luteinizing hormone, luteotropic hormone (prolactin), thyrotropic hormone, and adrenocorticotropic hormone.

The intermediate lobe is sandwiched between the anterior and posterior lobes. It has colloid-filled cysts. it elaborates melanocyte-stimulating hormone in some species (amphibia). In man and other mammals, the hormone appears to influence melanin synthesis.

The posterior lobe is made of sheets of cells and is rich in neurosecretory material. The latter is concentrated around the sinusoids. Two hormones have been extracted from this neurosecretory material, antidiuretic hormone and oxytocin.  

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