Plate 15.290 Pancreas
Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger,
Peer Review Status: Externally Peer Reviewed
Rhesus monkey, Helly's fluid, H. & E., 612 x.
Islet: Pale-staining area demarcated by arrows. Contains irregular clumps of cells. Separated from the acinar cells by a thin partition of reticular tissue. This endocrine gland elaborates the hormones insulin and glucagon, which are secreted into the rich capillary bed and carried via the portal system of veins into and through the hepatic lobules before reaching the general circulation. Insulin and glucagon constitute an important system for the regulation of blood glucose levels. This endocrine organ is essential for life. Dysfunction results in diabetes mellitus, a common disorder of man, characterized in its uncontrolled and most severe form by polyuria (frequent urination), polydipsia (excessive water intake), hyperglycernia (elevated glucose level in blood), glycosuria (sugar in the urine), ketonuria (ketones in the urine), acidosis (inability to buffer the blood at pH 7.2 to 7.4), wasting of the body and, if not treated, coma and death.
Acinar cells: Darker staining, irregular cells. Rich in cytoplasmic ribonucleic acid (RNA). Elaborate digestive enzymes, which are carried to, and are active in, the duodenum. Pancreatic enzymes break down partially digested food from the stomach into simple compounds. Carbohydrates, fats, and proteins are hydrolyzed by the enzymes amylase, lipase, and various proteases (including the nucleoproteases) secreted by the acinar cells.
Next Page | Previous Page | Section Top | Title Page
Please send us comments by filling out our Comment Form.
All contents copyright © 1995-2017 the Author(s) and Michael P. D'Alessandro, M.D. All rights reserved.
"Anatomy Atlases", the Anatomy Atlases logo, and "A digital library of anatomy information" are all Trademarks of Michael P. D'Alessandro, M.D.
Anatomy Atlases is funded in whole by Michael P. D'Alessandro, M.D. Advertising is not accepted.
Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.
The information contained in Anatomy Atlases is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.