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Anatomy Atlases: Atlas of Microscopic Anatomy: Section 1 - Cells Atlas of Microscopic Anatomy: Section 10 - Digestive System

Plate 10.202 Ileum

Ronald A. Bergman, Ph.D., Adel K. Afifi, M.D., Paul M. Heidger, Jr., Ph.D.
Peer Review Status: Externally Peer Reviewed

Peyer's patches

Plate 10.202 Ileum

Human, 10% formalin, H. & E., 20 x.


The ileum is the distal segment of the small intestine and differs from the other two segments in several ways. The duodenum is characterized by submucosal (Brunner's*) glands, which are absent from the jejunum and ileum. The jejunum may or may not have any submucosal lymphocytic aggregations. The submucosa of the ileum, however, normally does have aggregated lymphocytic nodules (Peyer's* patches) as well as extensive lymphocytic infiltration of the lamina propria. As a further comparison, the epithelial lining and submucosae of the different segments of the small intestine show a progressive increase in the number of goblet (mucous) cells and lymphatic tissue aggregates from duodenum to ileum.

*Both Brunner and Peyer were seventeenth-century Swiss anatomists.

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